|Lizzie (Radha Mitchell) longs to start a family with her husband Peter but is unable to conceive. Her best friend Andie (Michelle Monaghan), single and adrift, gets pregnant from a one-night stand and offers to give Lizzie the baby. Reluctantly, Peter agrees to be the childs father, and before he knows it Andie has moved into the guest room for the duration of her pregnancy. When Peter also invites his neer-do-well brother to the house, chaos ensues, testing the limits of friendship, family and a marriage. Expecting depicts the deeply human struggles of these four people, taking a funny and poignant look at the ways we try to plan ahead when life has something else in mind.